Progesterone acetate is a commonly used medication for women, mainly a type of progesterone that can control and regulate the menstrual cycle. So how much do we know about progesterone? Do you know the side effects of progesterone acetate?
The therapeutic range of progesterone acetate
Medroxyprogesterone is mainly used to treat dysmenorrhea, functional amenorrhea, functional uterine bleeding, threatened or habitual abortion, endometriosis, advanced breast cancer, endometrial adenocarcinoma and renal cancer.
Progesterone is highly soluble in chloroform, soluble in acetone, slightly soluble in ethyl acetate, slightly soluble in anhydrous ethanol, and insoluble in water. Progesterone is a progestogen drug with no estrogenic activity. The activity of progesterone is 20-30 times that of progesterone when injected subcutaneously, and intramuscular injection has a long-lasting effect.
Patients with thrombophlebitis, thromboembolic diseases, severe liver dysfunction, hypercalcemia, post abortion, uterine bleeding, pregnancy, or allergies to this product are prohibited from using it.
The administration method of progesterone acetate
Intramuscular injection, 10-20mg once.
(1) Habitual miscarriage: intramuscular injection of 10-20mg once a day or 2-3 times a week, until the fourth month of pregnancy.
(2) Dysmenorrhea: Inject 5-10mg daily 6-8 days before menstruation, for a total of 4-6 days, and the treatment can be repeated several times. Dysmenorrhea caused by underdeveloped uterus can be treated in combination with estrogen.
(3) Excessive menstrual bleeding and blood collapse: Daily intramuscular injection of 10-20mg, 5-7 days as a course of treatment, can be repeated 3-4 times, with an interval of 15-20 days between each course of treatment.
(4) Amenorrhea: After administering estrogen for 2-3 weeks, immediately administer 3-5mg of this product daily for 6-8 days as a course of treatment. The total dose should not exceed 300-350mg, and the course of treatment can be repeated 2-3 times.
Oral or vaginal administration: 100mg once, once in the morning and once in the evening (2 hours before bedtime), for 10 consecutive days per week (usually on the 17th to 26th day of the cycle).
The side effects of progesterone acetate
The side effects of progesterone include nausea, vomiting, dizziness, headache, and other adverse reactions;
It can also cause irregular bleeding and other reactions in women, as well as breast tenderness, bloating, and other phenomena. Its medication also includes a large amount of male hormones, and prolonged use during pregnancy may lead to the masculinization of female fetuses, especially when regulating the female menstrual cycle. It should be used with caution.
Moreover, patients with a history of depression should be carefully observed, and those with severe relapse of depression should stop taking medication. When some patients use progesterone, their tolerance to glucose decreases, so diabetes patients should use it with caution.
It is the function and use of progesterone, which can provide people with a lot of convenience, but it cannot be used at all times. It must be used under the guidance of a doctor and should not be taken indiscriminately.
