Bilateral choroidal plexus cysts in fetuses

  As is well known, bilateral choroidal plexus cysts are pseudocysts. Research has shown that the occurrence of bilateral choroidal plexus cysts in the human body is related to the rapid development of fetal brain primordia. Once bilateral choroidal plexus cysts occur, it has a certain impact on the future development of the fetus. So, what is the cause of bilateral choroidal plexus cysts?

  

Bilateral choroidal plexus cysts in fetuses1

  1. Choroidal cyst is a filling material that appears in the choroid plexus. Pseudocysts of cerebrospinal fluid are caused by the production of cerebrospinal fluid during fetal brain development, which has a higher pressure than cerebrospinal fluid. When the production rate of fetal cerebrospinal fluid is faster than the formation of the cerebral aqueduct system, it will cause a certain degree of cerebrospinal fluid circulation or blockage, forming choroid plexus cysts. However, typically the fetus develops a cerebral aqueduct system at around 26 weeks, so once a drainage system is formed, circulation issues will be immediately resolved, fluid accumulation will gradually disappear, and cysts will also disappear. If bilateral choroidal plexus cysts have not disappeared yet, it may be due to chromosomal diseases such as trisomy 21 and trisomy 18 in the fetus, requiring amniocentesis or umbilical cord blood puncture to rule out chromosomal abnormalities.

  2. The choroid plexus is a structural tissue rich in blood vessels. It is formed by the growth of venules into the ventricle and the extension of ventricular epithelium into the ventricle, and is the main structure for producing cerebrospinal fluid. It usually forms within 7 weeks of embryonic development. During the first 10-12 weeks of pregnancy, the choroid plexus is distributed throughout the entire lateral ventricle and gradually shrinks shortly thereafter. In mid pregnancy, approximately 1-2% of fetuses are detected with choroid plexus cysts. During 19-28 weeks of pregnancy, the loose choroidal villi of the choroid plexus will gradually be replaced by dense tissue, so most bilateral choroid plexus cysts usually disappear or shrink around 28 weeks of pregnancy, with only a few cysts remaining and continuing to grow.

  If the fetus is just a simple choroid plexus cyst, no special treatment is needed because such cysts will gradually disappear. Expectant mothers only need to have a B-ultrasound every 2 to 3 weeks to dynamically observe the cyst changes until delivery. In addition, children during their childhood should be tracked to monitor their neurological development. If the fetus has bilateral choroidal plexus cysts, it cannot be ruled out that it is caused by chromosomal abnormalities or deformities in the fetus. In this case, expectant mothers need to undergo amniocentesis or umbilical cord blood puncture to confirm if there are any abnormalities under the doctor's advice, and based on the puncture results, develop follow-up intervention plans.

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